Exosome therapy and PRP microneedling have transformed skin rejuvenation by using your skin cells’ natural growth factors and communication pathways. However, your results and recovery time depend heavily on proper aftercare. In this piece, you’ll find ideal post-treatment routines that can optimize your results, from the critical first 48 hours to long-term maintenance strategies for both therapies.
Immediate Post-Treatment Care (First 24–48 Hours)
Your body needs the first 48 hours after exosome or PRP treatment to get the best results. This time plays a vital role as your body starts its healing response.
Avoiding Sun Exposure and Heat Post Exosomes Therapy
Your skin enters a sensitive healing phase after exosome therapy. You need to protect it from anything that might stress it out. Stay away from direct sunlight for at least 24 to 48 hours after your treatment. The sun can irritate the treated area and make your therapy less effective.
Heat from other sources can damage your freshly treated skin as well. It increases inflammation and slows down healing. You should stay away from:
- Saunas, steam rooms, and hot tubs.
- Hot showers or baths (use lukewarm water instead).
- Heat styling tools if you had treatment on your scalp.
- Intense workouts that raise your body temperature.
Managing Redness and Swelling After PRP Treatment
Swelling and pain show that your healing process has started after PRP treatment. These symptoms are part of a normal inflammatory response that lasts a day or two after your procedure.
Here’s how you can handle these symptoms:
- Use ice packs in cycles (15 minutes on, 15 minutes off) to reduce swelling.
- Rest with your head propped up at a 30- to 45-degree angle using two pillows.
- Take paracetamol as your healthcare provider suggests.
- Drink 8 to 10 glasses of water.
Cleansing Routine: What to Use and Avoid
The right way to clean your skin matters after these treatments. PRP treatment needs four to six hours before you wash your face. This lets the plasma components sink in fully. Exosome treatments work best when you don’t touch or wash the treated area for 24 hours.
When you start cleaning:
- Pick gentle, non-irritating cleansers without fragrance, alcohol, and harsh chemicals.
- Use lukewarm water only.
- Pat your skin dry with a soft, clean towel instead of rubbing.
Stay away from these items for the first 48 hours:
- Oil-based skincare products
- Harsh cleansers, exfoliants, and retinoids
- AHAs/BHAs and vitamin C products
- Makeup
Skin Recovery Protocol for Days 3–7
Your skin enters a progressive healing phase during days three to seven after exosome or PRP therapy. The right care is vital as your skin rebuilds itself to achieve the best results.
Moisturization Guidelines for Exosomes and PRP Skin Treatment
Proper moisture levels form the foundation of your recovery during this vital phase. You might benefit from a prescribed post-treatment mask about three days after treatment to boost the hydrating effect of the exosomes or PRP. Your skin’s cellular regeneration depends on keeping it well-hydrated both inside and out.
To maximize hydration:
- Drink plenty of water throughout the day to flush toxins and help your skin heal.
- Use moisturizers that contain barrier-supporting ingredients like ceramides, peptides, or hyaluronic acid. Applying moisturizer twice daily helps maintain the right hydration levels during recovery.
- Think about products with occlusive agents that lock in moisture—such as petrolatum, vitamin E oil, and lanolin.
The Right Time to Resume Gentle Skincare Products
You can slowly bring back mild skincare products into your routine around day four. All the same, take this step carefully and systematically. Your skincare routine at this point might include:
- Gentle cleansing morning and evening with mild, fragrance-free products.
- Using prescribed serums or approved moisturizers.
- Gentle lymphatic drainage massage if your provider recommends it.
You might start using more of your regular skincare products between days five to seven if your skin shows normal healing progress. Although your skin may look better, you should still avoid harsh exfoliants, retinoids, and products with AHAs/BHAs until after the first week.
Products labeled for sensitive skin or made specifically for post-procedure care should be your priority. Ingredients like glycerin, aloe vera, and squalane provide hydration without irritation. Continuing to use only fragrance-free products reduces your risk of irritation.
Makeup Usage: When and How to Reintroduce
Most people can use mineral-based makeup after 48 hours have passed since the procedure, but some providers suggest waiting until redness or swelling goes away completely.
Tips for starting makeup again:
- Use clean brushes and applicators to avoid bacteria.
- Pick mineral-based or non-comedogenic products that keep pores clear.
- Pat products on gently instead of rubbing or dragging.
- Skip heavy foundations or products with alcohols, fragrances, or irritants.
Signs of Irritation and When to Contact Your Provider
Watching your skin for possible complications remains significant throughout recovery. Normal healing signs include:
- Steady improvement in the treated area.
- Less inflammation.
- Better skin texture.
- More comfort.
Some symptoms need immediate medical attention. Call the Beauty Vault team right away if you notice:
- Severe pain or pressure in the treated area.
- Major swelling that gets worse after 48 hours.
- Signs of infection (increased warmth, redness spreading beyond the injection site, pus or discharge).
- Allergic reactions.
- Fever or chills.
You should also ask your provider about ongoing mild discomfort, unusual healing patterns, or questions about your recovery. However, note that temporary itching or dryness often occurs during healing. Don’t scratch or pick at your skin as this can disrupt healing and possibly cause scarring.
Long-Term Maintenance and Follow-Up Care
Your results will last longer after recovery when you commit to regular follow-up care and healthy lifestyle choices. A proper maintenance schedule will help your regenerative treatments deliver lasting benefits.
Scheduling Follow-Up Sessions for PRP Therapy
PRP follow-up sessions work best with a specific timing pattern. Your first three sessions should be four to six weeks apart. This gives your body time to respond to each treatment and build on previous results.
You should schedule an assessment two to four months after completing your original treatment series. This helps the Beauty Vault team see how well the treatments worked and plan next steps. You may also benefit from scheduling sessions every six months for long-term maintenance.
How Often to Repeat Exosomes Treatment
Exosome therapy needs a different approach than PRP. Most providers recommend three to four treatments with four-week gaps between sessions. This timing maximizes the regenerative benefits from each treatment.
After your original series, you might need maintenance treatments every four to five months. Some providers adjust this to every six to eight weeks based on your needs and how well you respond.
Note that lasting changes usually need the complete treatment plan, even though you might see improvements after one session.
Lifestyle Habits That Support Skin Regeneration
Your daily habits can significantly boost your treatment results:
- Hydration: Your cells and skin need plenty of water each day.
- Balanced nutrition: Your diet should be rich in vitamins, minerals, antioxidants, and omega-3 fatty acids.
- Quality sleep: Your body needs seven to eight hours of sleep for repair and renewal.
- Stress management: You can try meditation or hobbies to reduce the effects of stress on your skin.
- Regular exercise: Physical activity helps blood flow and nutrient delivery to your skin.
- Sun protection: Your treated areas need consistent SPF protection.
These lifestyle changes work together with your treatments to keep your skin healthy and extend your results.
Get Advice from the Beauty Vault About Aftercare for Exosomes and PRP
Good aftercare greatly affects the outcome of your exosome and PRP treatments. Your recovery needs specific care at each stage. The Beauty Vault team is happy to guide and prepare you in preserving your results before starting any regenerative treatment. In fact, they can create a customized plan for your skin concerns and help you through recovery. If you’re ready to get started, call them now at (323) 800-6770 or fill out a contact form.
FAQs
Q1. What are the key aftercare steps following exosome treatment?
After exosome treatment, avoid washing your face for six hours to allow the exosomes to absorb. You can apply moisturizer and makeup after 24 hours. Avoid sun exposure, heat, and other facial treatments for the first 72 hours. Stay hydrated and follow a gentle skincare routine.
Q2. How should I care for my skin immediately after PRP therapy?
Post-PRP, use acetaminophen for pain relief instead of anti-inflammatory medications. Apply ice to the treated area for 15 to 20 minutes every two to four hours during the first few days. Minimize activity and avoid heat exposure. You can shower, but be gentle when cleansing the treated area.
Q3. What should I avoid after receiving exosome or PRP treatment?
After these treatments, avoid sun exposure, heat sources (like saunas or hot showers), strenuous exercise, and sweating for at least 24 to 48 hours. Don’t use harsh skincare products, exfoliants, or retinoids for about a week. Refrain from applying makeup for the first 48 hours, depending on your provider’s instructions.
